Cold-Chain Items

Introduction

When drafting Drug Album project, I suddenly have a thought of tabulating a list of medications that have to be refrigerated. Theoretically, this piece of information may smoothen the process of searching an unknown drug.

In my reading, there are few important key points that I come to realise.

  • Medications that have to be refrigerated are mainly injections, which comprises of insulins, vaccines, immunoglobulins and biologics.
  • The storage condition of a medicine can vary across brands. For example,
    • Fludarabine injection - store under refrigeration or at room temperature, as specified according to manufacturer's labelling.
    • Although Dalacin C (Clindamycin) injection have to be kept at refrigerator, but there are brands which can be kept at room temperature.
  • The storage condition of a medicine can vary across dosage forms.
    • Alfacalcidol (One-Alpha)
      • Capsule: Store below 30°C.
      • Drops and Solution for injection: Store at 2-8°C.
    • Busulfan (Myleran)
      • Tablet:Store below 30°C.
      • Injection: Store in a refrigerator (2-8°C)
    • Isavuconazole (Cresemba)
      • Capsule: Store below 30°C.
      • IV: Store in a refrigerator (2-8°C)
    • Lopinavir/Ritonavir (Kaletra)
      • Tablet: No special storage condition.
      • Oral solution: Store in a refrigerator (2-8°C)
    • Risperidone
      • Risperdal oral solution and tablet: Store below 30°C.
      • Risperdal Consta injection: Store at refrigerator (2-8°C).

Below is a summary list of medications that should ideally be stored at 2-8°C prior dispensing to patients.

  • In-use stability data (including post reconstitution) is not considered. To illustrate, some medications, such as insulin, can be stored at room temperature for a short period of time after they have been removed from the refrigerator.
  • If needed, you may refer product leaflet for further recommendations on stability at room temperature (usually much shorter than at refrigerator) and in-use stability data (including post reconstitution).



Non Injectables

Oral

  • Alfacalcidol 2 mcg/ml Drops (One-Alpha)
  • Chlorambucil 2 mg Tablet (Leukeran)
  • Diclofenac Resinate 1.5% Oral Drop Suspension (Cataflam)
  • Lopinavir 80 mg/Ritonavir 20 mg (per ml) Oral Solution (Kaletra)
  • Melphalan 2 mg Tablet (Alkeran)
  • Risdiplam 0.75 mg/ml Solution (Evrysdi)
  • Zuclopenthixol 20 mg/ml Drops (Clopixol)
Topical

  • Clindamycin 1% and Benzoyl Peroxide 5% Gel (Duac)
  • Fluocinolone Acetonide 0.01%, Hydroquinone 4% and Tretinoin 0.05% Cream (Tri-Luma)

Eye

  • Chloramphenicol 0.5% Eye Drop (Nicol, Shinacol, Xepanicol)
  • Latanoprost 0.005% and Timolol Maleate 0.5% Eye Drop (Xalacom, Latamolol)
  • Latanoprost 0.005% Eye Drop (Xalatan)
  • Omidenepag Isopropyl 0.002% Ophthalmic Solution (Eybelis)
  • Proparacaine HCl 0.5% Ophthalmic Drop (Alcaine)
  • Tafluprost 0.0015% Ophthalmic Solution (Preservative Free) (Taflotan-S)
  • Tafluprost 0.0015% and Timolol 0.5% Ophthalmic Solution (Preservative Free) (Tapcom-S)

Ear

  • Chloramphenicol 5% Ear Drop (Enclor, Nicol, Xepanicol)

Inhalers

  • Beclomethasone Dipropionate 100 mcg and Formoterol Fumarate Dihydrate 6 mcg MDI (Foster)
  • Beclomethasone Dipropionate 100 mcg, Formoterol Fumarate Dihydrate 6 mcg and Glycopyrronium Bromide 12.5 mcg MDI (Trimbow)

Rectal

  • Hydrocortisone 5 mg, Cinchocaine HCl 5 mg, Framycetin Sulphate 10 mg and Aesculin 10 mg Suppository (Proctosedyl)
  • Hydrocortisone Acetate 7.5 mg, Benzocaine 40 mg and Zinc Oxide 250 mg Suppository (Doproct)
  • Lignocaine, Aluminium Acetate, Zinc Oxide and Hydrocortisone Ointment (Xyloproct)
  • Lignocaine, Aluminium Acetate, Zinc Oxide and Hydrocortisone Suppository (Xyloproct, Liproct)

Vaginal

  • Dinoprostone 3 mg Vaginal Tablet (Prostin E2)
  • Gemeprost (Prostaglandin E1 Synthetic Analogue) 1 mg Pessary (Cervagem) - Frozen at -10°C
  • Lactobacillus acidophilus 100 million viable cells and Estriol 003 mg Vaginal Tablet (Gynoflor)



Insulins

Prandial

  • Insulin Aspart 100 IU/ml Injection (Pre-filled Pen/Penfill) (Novorapid, Fiasp)
  • Insulin Glulisine 100 IU/ml Solution for Injection in Pre-filled Pen (Apidra)
  • Insulin Lispro 100 IU/ml Injection in Pre-filled Syringe/Cartridge (Humalog)
  • Insulin Recombinant Neutral Human Short Acting 100 IU/ml Injection in 10 ml Vial (Actrapid, Humulin R)
  • Insulin Recombinant Neutral Human Short-Acting 100 IU/ml Penfill and Refill (Actrapid, Humulin R, Insugen R)

Basal

  • Insulin Degludec 100 IU/ml Injection (Tresiba)
  • Insulin Degludec 200 IU/ml Injection (Tresiba)
  • Insulin Detemir 100 IU/ml Injection in Pre-filled Syringe/Cartridge (Levemir)
  • Insulin Glargine 300 IU/3ml Injection (Pre-filled Pen) (Lantus Solostar, Basalog One)
  • Insulin Glargine 300 IU/ml Injection (Pre-filled Pen) (Toujeo)
  • Insulin Recombinant Synthetic Human Intermediate-Acting 100 IU/ml in Vial for Injection (Insulatard, Humulin N)
  • Insulin Recombinant Synthetic Human, Intermediate-Acting 100 IU/ml Penfill and Refill (Insulatard, Humulin N, Insugen-N)

Premixed

  • Insulin Aspart 30% and Protaminated Insulin Aspart 70% 100 IU/ml Injection (FlexPen) (Novomix 30)
  • Insulin Degludec 70% and Insulin Aspart 30% 100 IU/ml Injection in Pre-filled Pen (Ryzodeg)
  • Insulin Glargine 100 IU and Lixisenatide 33 mcg per ml Injection (Pre-filled Pen) (Soliqua 30-60)
  • Insulin Glargine 100 IU and Lixisenatide 50 mcg per ml Injection (Pre-filled Pen) (Soliqua 10-40)
  • Insulin Lispro 25% and Insulin Lispro Protamine 75% 100 IU/ml Suspension for Injection in Prefilled Syringe/Cartridge (Humalog Mix 25)
  • Insulin Lispro 50% and Insulin Lispro Protamine 50% 100 IU/ml Suspension for Injection in Prefilled Syringe/Cartridge (Humalog Mix 50)
  • Insulin Recombinant Synthetic Human Premixed 100 IU/ml in Vial for Injection (Mixtard, Humulin 30/70)
  • Insulin Recombinant Synthetic Human, Premixed 100 IU/ml Penfill and Refill (Mixtard, Humulin 30/70, Insugen-30/70)



Vaccines

  • BCG Vaccine Freeze-Dried Injection
  • Cholera Vaccine Oral Suspension (Dukoral)
  • Diphtheria, Tetanus, Pertussis (Acellular component), Hepatitis B (rDNA), Poliomyelitis (Inactivated) and Haemophilus Influenzae Type B Conjugate Vaccine (adsorbed) Injection (Hexaxim)
  • Diphtheria, Tetanus Toxoids and Acellular Pertussis Vaccine Injection (Adacel, Boostrix)
  • Haemophilus Influenza Type B Conjugate Vaccine Injection (Hiberix)
  • Hepatitis A Vaccine Injection (Avaxim)
  • Hepatitis B Vaccine Injection (Engerix-B, Euvax-B)
  • Human Papillomavirus (Types 16, 18) Vaccine Injection (Cervarix)
  • Human Papillomavirus (Types 6, 11, 16, 18) Vaccine Injection (Gardasil)
  • Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45,52, 58) Vaccine Injection (Gardasil 9)
  • Influenza Vaccine (Inactivated) Injection (VaxigripTetra, Fluarix Tetra)
  • Japanese Encephalitis (Live Attenuated) Vaccine Injection (Imojev)
  • Measles, Mumps and Rubella (MMR) Vaccine Injection (Priorix)
  • Measles, Mumps, Rubella and Varicella Virus Vaccine Injection (ProQuad)
  • Meningococcal Group A, C, Y, W135 Vaccine Injection (Nimenrix, Menveo)
  • Pneumococcal Polysaccharide and Non-Typeable Haemophilus Influenzae Protein D Conjugate Vaccine (10-Valent, Adsorbed) (Synflorix)
  • Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) 13-Valent Injection (Prevenar 13)
  • Pneumococcal Vaccine (Polyvalent) (Pneumo 23, Pneumovax 23)
  • Rabies Vaccine Injection (Verorab)
  • Rotavirus Vaccine (Oral) 2 ml Pre-filled Dosing Tube (RotaTeq)
  • Typhoid Vaccine Capsule (Vivotif)
  • Varicella Virus Vaccine Live Attenuated Injection (Varivax, Varilrix)



Immunoglobulins

  • Anti-D Immunoglobulin Injection (Rhesonativ)
  • Antirabies Immunoglobulin Injection (Imogam Rabies)
  • Antithymocyte Immunoglobulin (from Horse) Injection (Atgam)
  • Antithymocyte Immunoglobulin (from Rabbit) Injection (Thymoglobuline)
  • Hepatitis B Immunoglobulin (Human) Injection (Hyperhep, Hepabig)
  • Tetanus Human Immunoglobulin 250 IU/Vial Injection (Sero-Tet)
  • Varicella Zoster Immunoglobulin (Human) 25 IU/ml Solution for Infusion (Varitect CP)



Epoetins

Darbepoetin Alfa

  • Darbepoetin Alfa 120 mcg/0.5 ml Injection (NESP)
  • Darbepoetin Alfa 20 mcg/0.5 ml Injection (NESP)
  • Darbepoetin Alfa 40 mcg/0.5 ml Injection (NESP)

Epoetin Alfa

  • Epoetin Alfa 10000 IU Injection (Eprex)
  • Epoetin Alfa 1000 IU Injection (Eprex)
  • Epoetin Alfa 2000 IU Injection (Eprex, Erysaa)
  • Epoetin Alfa 3000 IU Injection (Eprex)
  • Epoetin Alfa 4000 IU Injection (Eprex, Erysaa)

Epoetin Beta

  • Epoetin Beta 4000 IU Injection (Recormon)
  • Epoetin Beta 2000 IU Injection (Recormon)

Methoxyl Polyethylene Glycol-epoetin Beta

  • Methoxyl Polyethylene Glycol-epoetin Beta 100 mcg/0.3 ml Injection in Prefilled Syringe (Mircera)
  • Methoxyl Polyethylene Glycol-epoetin Beta 120 mcg/0.3 ml Injection in Prefilled Syringe (Mircera)
  • Methoxyl Polyethylene Glycol-epoetin Beta 150 mcg/0.3 ml Injection in Prefilled Syringe (Mircera)
  • Methoxyl Polyethylene Glycol-epoetin Beta 200 mcg/0.3 ml Injection in Prefilled Syringe (Mircera)
  • Methoxyl Polyethylene Glycol-epoetin Beta 50 mcg/0.3 ml Injection in Prefilled Syringe (Mircera)
  • Methoxyl Polyethylene Glycol-epoetin Beta 75 mcg/0.3 ml Injection in Prefilled Syringe (Mircera)



Neuromuscular Blocker

  • Atracurium Besilate 10 mg/ml in 2.5 ml Injection (Tracrium, Notrixum)
  • Atracurium Besilate 10 mg/ml in 5 ml Injection (Tracrium, Notrixum)
  • Cisatracurium Besilate 2 mg/ml Injection (Nimbex)
  • Mivacurium 2 mg/ml Injection (Mivacron)
  • Pancuronium Bromide 2 mg/ml Injection (Pravulon)
  • Rocuronium Bromide 10 mg/ml Injection (Esmeron)



Blood Products

  • Factor IX, Factor II and Factor X in combination 500 IU/vial Injection (Prothrombinex-VF)
  • Factor VIII (Human Blood Coagulation Factor) and Von Willebrand Factor Injection (Biostate)
  • Factor IX Injection (AlphaNine SD)
  • Nonacog Alfa 1000 IU Injection (BeneFIX)
  • Nonacog Alfa 2000 IU Injection (BeneFIX)
  • Nonacog Alfa 250 IU Injection (BeneFIX)
  • Nonacog Alfa 500 IU Injection (BeneFIX)
  • Recombinant Factor VIII 250 IU Injection (Advate, Xyntha)
  • Recombinant Factor VIII 500 IU Injection (Advate, Xyntha)



Enzymes

  • Agalisdase Beta 5 mg Injection (Fabrazyme)
  • Agalisdase Beta 35 mg Injection (Fabrazyme)
  • Alglucosidase Alfa 5 mg/ml Injection (Myozyme)
  • Elosulfase Alfa 1 mg/ml Injection (Vimizim)
  • Idursulfase 2 mg/ml Injection (Elaprase)
  • Imiglucerase 400 IU Injection (Cerezyme)
  • Laronidase 2.9 mg/5 ml Injection (Aldurazyme)



Interferons

Interferon Beta-1a

  • Interferon Beta-1a 22 mcg Injection (Rebif)
  • Interferon Beta-1a 44 mcg Injection (Rebif)

Peginterferon Alfa-2a

  • Peginterferon Alfa-2a 135 mcg Prefilled Syringe (Pegasys)
  • Peginterferon Alfa-2a 180 mcg Prefilled Syringe (Pegasys)

Peginterferon Alfa-2b

  • Peginterferon Alfa-2b 100 mcg Injection (Peg-Intron)
  • Peginterferon Alfa-2b 120 mcg Injection (Peg-Intron)
  • Peginterferon Alfa-2b 150 mcg Injection (Peg-Intron)
  • Peginterferon Alfa-2b 50 mcg Injection (Peg-Intron)
  • Peginterferon Alfa-2b 80 mcg Injection (Peg-Intron)



Antimicrobials

Antibacterial

  • Cefotolazone 1000 mg and Tazobactam 500 mg Injection (Zerbaxa)
  • Clindamycin Phosphate 150 mg/ml Injection (Dalacin C)
  • Daptomycin 500 mg Injection (Cubicin)

Antifungals

  • Amphotericin B 50 mg Injection (Conventional)
  • Anidulafungin 100 mg Injection (Eraxis)
  • Caspofungin Acetate 50 mg Injection (Cancidas)
  • Caspofungin Acetate 70 mg Injection (Cancidas)
  • Isavuconazole 200 mg Infusion Concentrate (Cresemba)



Chemotherapy

Alkylating Agents

  • Busulfan 6 mg/ml Injection (Myleran)
  • Carmustine 100 mg Injection (BiCNU)
  • Carmustine 7.7 mg Implant (Gliadel Wafer Implant) - Store in a freezer (-20°C)
  • Dacarbazine 100 mg Injection

Anthracyclines

  • Doxorubicin HCl 2 mg/ml Injection (Adriamycin) - Solution
  • Epirubicin 2 mg/ml Injection (Pharmorubicin) - Solution
  • Idarubicin 1 mg/ml Injection (Zavedos)
  • Pegylated Liposomal Doxorubicin HCl 20 mg/Vial (Caelyx)

Vinca Alkaloids

  • Vinblastine Sulphate 1 mg/ml Injection (Velbe)
  • Vincristine Sulphate 1 mg/ml Injection (Oncovin, Vinracine)
  • Vinorelbine 10 mg/ml Injection (Navelbine, Vinelbine)

Others

  • Carfilzomib 60 mg/vial Powder for Solution for Infusion (Kyprolis)
  • L-asparaginase 10000 IU Injection (Leunase)
  • Pegaspargase 750 U/ml Powder for Solution for Injection/Infusion (Oncaspar)



Obstetrics and Gynaecology

Gonadotrophins

  • Choriogonadotropin Alfa 250 mcg/0.5 ml Injection in Prefilled Syringe (Ovidrel)
  • Corifollitropin Alfa 100 mcg/0.5 ml Solution for Injection (Elonva)
  • Corifollitropin Alfa 150 mcg/0.5 ml Solution for Injection (Elonva)
  • Follitropin Alfa (Recombinant Human FSH) 300 IU/0.5 ml Injection (Gonal F)
  • Follitropin Alfa (Recombinant Human FSH) 75 IU Injection (Gonal F)
  • Follitropin Beta (Recombinant Human FSH) 300 IU Injection (Puregon)
  • Follitropin Beta (Recombinant Human FSH) 50 IU Injection (Puregon)
  • Follitropin Delta 12 mcg/0.36 ml Solution for Injection (Rekovelle)
  • Follitropin Delta 36 mcg/1.08 ml Solution for Injection (Rekovelle)
  • Follitropin Delta 72 mcg/2.16 ml Solution for Injection (Rekovelle)
  • Human Chorionic Gonadotrophin 5000 IU Injection (Pregnyl)
  • Menotropin, Highly Purified 150 IU Injection (HuMoG)
  • Menotropin, Highly Purified 75 IU Injection (HuMoG)
  • Urofollitropin (FSH) 150 IU Injection (Foliculin)
  • Urofollitropin (FSH) 75 IU Injection (Foliculin)

Oxytocins

  • Oxytocin 10 Units/ml Injection (Syntocinon, Udoxan)
  • Oxytocin 5 Units and Ergometrine Maleate 0.5 mg per ml Injection (Syntometrine)

Others

  • Carboprost Tromethamine 250 mcg Injection (Hemabate)
  • Cetrorelix 0.25 mg Injection (Cetrotide)
  • Fulvestrant 250 mg/5 ml Solution for Injection (Faslodex, Eranfu)



Endocrinology

GLP-1 Agonists

  • Dulaglutide 0.75 mg Solution for Injection in Pre-filled Pen (Trulicity)
  • Dulaglutide 1.5 mg Solution for Injection in Pre-filled Pen (Trulicity)
  • Exenatide 2 mg Powder and Solvent for Prolonged Release Suspension for Injection (Bydureon)
  • Liraglutide 6 mg/ml Preloaded Injector (Victoza, Saxenda)
  • Lixisenatide 10 mcg/0.2 ml Solution for Injection 3 ml Prefilled Pen (Lyxumia)
  • Lixisenatide 20 mcg/0.2 ml Solution for Injection 3 ml Prefilled Pen (Lyxumia)
  • Semaglutide 1.34 mg per ml Solution for Injection Pre-filled Pen (Ozempic 0.25 mg, 0.5 mg per dose, Ozempic 1 mg per dose)

Somatostatin Analogues

  • Lanreotide Autogel 60 mg/0.5 ml Prolonged-release Solution for Injection in a Prefilled Syringe (Somatuline Autogel)
  • Lanreotide Autogel 90 mg/0.5 ml Prolonged-release Solution for Injection in a Prefilled Syringe (Somatuline Autogel)
  • Lanreotide Autogel 120 mg/0.5 ml Prolonged-release Solution for Injection in a Prefilled Syringe (Somatuline Autogel)
  • Octreotide 0.05 mg/ml Injection (Sandostatin)
  • Octreotide 0.1 mg/ml Injection (Sandostatin)
  • Octreotide Acetate 20 mg Injection (Sandostatin LAR)
  • Octreotide Acetate 30 mg Injection (Sandostatin LAR)

Somatropins

  • Somatropin 6 mg Solution for Injection (Saizen)
  • Somatropin 10 mg (30 IU) Injection (Norditropin NordiFlex)
  • Somatropin 12 mg (36 IU) Injection (Genotropin GoQuick)
  • Somatropin 5 mg (15 IU) Injection (Norditropin NordiFlex)
  • Somatropin 8 mg (24 IU) Injection (Saizen)

Bone Resorption Inhibitors

  • Calcitonin (Synthetic Salmon) 100 IU Injection (Miacalcic)
  • Calcitonin (Synthetic Salmon) 50 IU Injection (Miacalcic)
  • Etelcalcetide 5 mg/ml Solution for Injection Vial (Parsabiv)

Vasopressin and Analogues

  • Desmopressin Acetate 4 mcg/ml Injection (Minirin)
  • Terlipressin 1 mg Injection (Glypressin)
  • Vasopressin 20 Units/ml Injection

Others

  • Alfacalcidol 2 mcg/ml Injection (One-Alpha)
  • Glucagon (Lyophilised) 1 mg/ml Injection (GlucaGen)
  • Synthetic ACTH (Tetracosactrin Acetate) 250 mg/ml Injection (Synacthen)
  • Teriparatide Solution for Injection (Pre-filled Pen) 20 mcg/80 microlitre Injection (Forteo, Sondelbay)
  • Thyrotropin Alfa 0.9 mg/ml Injection (Thyrogen)



Biologics

PCSK9 Inhibitor

  • Alirocumab 75 mg Injection (Prefilled Pen/Syringe) (Praluent)
  • Alirocumab 150 mg Injection (Prefilled Pen/Syringe) (Praluent)
  • Evolocumab 140 mg Injection (Pre-filled Autoinjector/Syringe) (Repatha)

Calcitonin Gene--related Peptide Inhibitors

  • Erenumab 70 mg/ml Solution for Injection in a Pre-filled Syringe (Pasurta)
  • Erenumab 140 mg/ml Solution for Injection in a Pre-filled Syringe (Pasurta)
  • Galcanezumab 120 mg/ml Solution for Injection in Pre-filled Pen (Emgality, Pontevia)
  • Galcanezumab 120 mg/ml Solution for Injection in Pre-filled Syringe (Emgality, Pontevia)

TNF-Alpha Inhibitors

  • Adalimumab 40 mg Injection (Humira)
  • Certolizumab Pegol 200 mg/ml Injection (Cimzia)
  • Etanercept 25 mg Injection (Enbrel)
  • Etanercept 50 mg Injection (Enbrel)
  • Golimumab 50 mg Solution for Injection in Pre-filled Syringe (Simponi)
  • Infliximab 100 mg Injection (Remicade, Remsima)

Vascular Endothelial Growth Factor Inhibitors

  • Aflibercept 25 mg/ml Concentrate for Solution for Infusion (Zaltrap)
  • Aflibercept 40 mg/ml Solution Vial for Injection (Eylea)
  • Brolucizumab 120 mg/ml Injection (Pagenax)
  • Ranibizumab 10 mg/ml Injection (Accentrix)

Interleukin Inhibitors

  • Brodalumab 210 mg/1.5 ml Prefilled Syringe (Lumicef)
  • Dupilumab 200 mg Solution for Injection Pre-filled Syringe (Dupixent)
  • Dupilumab 300 mg Solution for Injection Pre-filled Syringe (Dupixent)
  • Guselkumab 100 mg/ml Solution for Injection (Tremfya)
  • Ixekizumab 80 mg/ml Solution for Injection in Pre-filled Pen (Taltz)
  • Ixekizumab 80 mg/ml Solution for Injection in Pre-filled Syringe (Taltz)
  • Risankizumab 75 mg/0.83 ml Solution for Injection in Pre-filled Syringe (Skyrizi)
  • Secukinumab 150 mg/ml Injection (Cosentyx)
  • Tocilizumab 162 mg/0.9 ml Solution for Injection in Prefilled Syringe (SC) (Actemra)
  • Tocilizumab 20 mg/ml Injection (Actemra)
  • Ustekinumab 90 mg/ml Injection (Stelara)

Monoclonal Antibodies, Anti-lymphocyte

  • Alemtuzumab 10 mg/ml Concentrate for Solution for Infusion (Lemtrada)
  • Basiliximab 20 mg Injection (Simulect)
  • Belimumab 120 mg Powder for Solution for Infusion (Benlysta)
  • Vedolizumab 300 mg Powder for Concentrate for Solution for Infusion (Entyvio)

Monoclonal Antibodies

  • Atezolizumab 60 mg/ml Concentrate for Solution for Infusion (Tecentriq)
  • Avelumab 200 mg/10 ml Concentrate for Solution for Infusion (Bavencio)
  • Benralizumab 30 mg/ml Solution for Injection (Fasenra)
  • Bevacizumab 25 mg/ml Injection (Avastin)
  • Blinatumomab 35 mcg Powder for Infusion (Blincyto)
  • Brentuximab Vedotin 50 mg Powder for Infusion (Adcetris)
  • Cetuximab 5 mg/ml Solution for Infusion (Erbitux)
  • Daratumumab 20 mg/ml Concentrate for Solution for Infusion (Darzalex)
  • Denosumab in 1.0 ml Solution (60 mg/ml) Pre-filled Syringe (Subcutaneous Injection) (Prolia)
  • Denosumab 120 mg/1.7 ml Solution for Injection Vial (Subcutaneous Injection) (Xgeva)
  • Durvalumab 50 mg/ml Concentrate for Solution for Intravenous Infusion (Imfinzi)
  • Emicizumab 30 mg/ml Solution for Injection (Hemlibra)
  • Emicizumab 150 mg/ml Solution for Injection (Hemlibra)
  • Nivolumab 10 mg/ml Concentrate for Solution for Infusion (Opdivo)
  • Omalizumab 150 mg Powder and Solvent for Solution (Xolair)
  • Obinutuzumab 25 mg/ml Concentrate for Solution for Infusion (Gazyva)
  • Omalizumab 150 mg Powder and Solvent for Solution (Xolair)
  • Palivizumab 100 mg Injection (Synagis)
  • Pantimumab 20 mg/ml Concentrate for Solution for Infusion (Vectibix)
  • Pembrolizumab 25 mg/ml Solution for Infusion (Keytruda)
  • Pertuzumab 30 mg/ml Concentrate for Solution for Infusion (Perjeta)
  • Polatuzumab Vedotin 140 mg Powder for Infusion (Polivy)
  • Ramucirumab 10 mg/ml Injection (Cyramza)
  • Rituximab 10 mg/ml Injection (Mabthera IV)
  • Rituximab 1400 mg/11.7 ml Solution for Subcutaneous Injection (Mabthera SC)
  • Romosozumab 105 mg/1.17 ml Solution for Injection in Pre-filled Syringe (Evenity)
  • Satralizumab 120 mg/ml Injection in Prefilled Syringe (Enspryng)
  • Siltuximab 100 mg Powder for Concentrate for Solution for Infusion (Sylvant)
  • Siltuximab 400 mg Powder for Concentrate for Solution for Infusion (Sylvant)
  • Trastuzumab 440 mg Injection (Herceptin)
  • Trastuzumab 600 mg/5 ml Solution for Injection (for Subcutaneous) (Herceptin)
  • Trastuzumab Emtansine 100 mg Powder for Infusion (Kadcyla)
  • Trastuzumab Emtansine 160 mg Powder for Infusion (Kadcyla)



Miscellaneous

  • Alprostadil 500 mcg/ml Injection (Prostin VR)
  • Andexanet Alfa 200 mg Powder for Solution for Infusion Vials (Ondexxya)
  • Beractant Intrathecal Suspension (200 mg phospholipids in 8 ml vial) (Survanta)
  • Clostridium botulinum Toxin Type A 100 Units (Botox)
  • Clostridium botulinum Type A Toxin Haemagglutinin Complex 300 Units/Vial Powder for Injection (Dysport)
  • Clostridium botulinum Type A Toxin Haemagglutinin Complex 500 Units/Vial Powder for Injection (Dysport)
  • Digoxin Immune Fab 40 mg/vial Powder for Solution for Infusion (DigiFab)
  • Filgrastim (G-CSF) 30 MU in 0.5 ml Injection (Neupogen)
  • Filgrastim (G-CSF) 30 MU/ml Injection (Neupogen)
  • Leucovorin Calcium 3 mg Injection - Solution for Injection
  • Leucovorin Calcium 50 mg Injection - Solution for Injection
  • Leuprolide 22.5 mg Injection (Eligard)
  • Pegfilgrastim Pre-filled Syringe 6 mg/0.6 ml (Neulastim, Fulphila)
  • Risperidone 25 mg Injection (Long Acting) (Risperdal Consta)
  • Risperidone 37.5 mg Injection (Long Acting) (Risperdal Consta)
  • Risperidone 50 mg Injection (Long Acting) (Risperdal Consta)
  • Romiplostim 250 mcg Injection (Romiplate)
  • Suxamethonium Chloride 50 mg/ml Injection (Scoline)
  • Tuberculine PPD Injection

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